Quellen und Studienauswahl

Literatur

  • DGE, Referenzwerte für die Nährstoffzufuhr. Neuer Umschau Buchverlag, Neustadt an der Weinstrasse, 1. Auflage, 3. Korrigierter Nachdruck (2008), Aktualisierung vom Dezember 2011 
  • Burgerstein - Handbuch Nährstoffe, 12. Auflage, TRIAS-Verlag
  • Physiologie des Menschen, Schmitt/Thews, 27. Auflage, Springer-Verlag
  • Basiswissen Biochemie mit Pathobiochemie, 3. Auflage, Löffler-Verlag
  • Endokrinologie für die Praxis, Thieme 2010, 6.Auflage, Diagnostik und Therapie von A-Z
  • Endokrinologie und Stoffwechsel, Thieme Verlag 2011, 2. Auflage
  • Amboss - Fachwissen für Mediziner
  • Kyra Kauffmann, Jod - Das Standardwerk zum vergessenen Heilmittel, ISBN-10: 3958141188, ISBN-13:978-3958141186, Riva (2019) E-Book-Version
  • Dr. Datis Kharrazian - Schilddrüsenunterfunktion und Hashimoto anders behandeln, ISBN-10:9783867311205, ISBN-13:978-3867311205, VAK (2016) E-Book-Version
  • Dr. med. Berndt Rieger- Hashimoto-Healing, ISBN-10:3868825878, ISBN-13:978-3868825879, mvg-Verlag (2015)
  • Dr. med. Berndt Rieger - Die heimlichen Chefs im Körper, ISBN-10:3868829598, ISBN-13:987-3868829594, mvg-Verlag (2018)

Doktorarbeiten

  • TU-München, Selen und Hashimoto, 2017, Nina Hellwig 
  • Uni Erlangen, Hashimoto und psychische Störungen, Silke Schinhammer 

Studien Hashimoto und Vitamin D

  • 2019 Sep 25;47(279):111-113. [Vitamin D and Hashimoto's disease] [Article in Polish]

Małgorzata Jamka 1, Marek Ruchała 2, Jarosław Walkowiak 1
Affiliations expand 
PMID: 31557141


  • 2017 Jun;24(2):53-62. Relevance of 25 (OH) Vitamin D deficiency on Hashimoto's Thyroiditis

Hoda G Bakr 1, Takwa E Meawed 2 Affiliations expand

PMID: 29528579

  • 2015 Sep;94(39):e1639.  doi: 10.1097/MD.0000000000001639.

Lower Serum 25-Hydroxyvitamin D Level is Associated With 3 Types of Autoimmune Thyroid Diseases

Jie Ma 1, Di Wu, Chenyang Li, Chenling Fan, Nannan Chao, Jing Liu, Yushu Li, Renee Wang, Wei Miao, Haixia Guan, Zhongyan Shan, Weiping Teng

Affiliations expand

PMID: 26426654  PMCID: PMC4616844  DOI: 10.1097/MD.0000000000001639

  • 2020 Apr;43(4):413-429.  doi: 10.1007/s40618-019-01123-5. Epub 2019 Oct 4.

Immunomodulatory effect of vitamin D and its potential role in the prevention and treatment of thyroid autoimmunity: a narrative review

D Gallo 1, L Mortara 2, M B Gariboldi 3, S A M Cattaneo 4, S Rosetti 1, L Gentile 1, D M Noonan 2 5, P Premoli 1, C Cusini 1, M L Tanda 1, L Bartalena 6, E Piantanida 7

Affiliations expand

PMID: 31584143  DOI: 10.1007/s40618-019-01123-5


  • 2019 Jun;100:7-16. doi: 10.1016/j.jaut.2019.03.002. Epub 2019 Mar 8. 

Immunological effects of vitamin D and their relations to autoimmunity 

Erin Yamamoto 1, Trine N Jørgensen 2 

Affiliations expand 

PMID: 30853311 DOI: 10.1016/j.jaut.2019.03.002 

 

  • 2017 Sep;18(3):347-354. doi: 10.1007/s11154-017-9406-3. 

Sunshine vitamin and thyroid 

Immacolata Cristina Nettore 1, Luigi Albano 2, Paola Ungaro 3, Annamaria Colao 1, Paolo Emidio Macchia 4 

Affiliations expand 

PMID: 28092021 PMCID: PMC5543192 DOI: 10.1007/s11154-017-9406-3 

  • 2020 Mar 17;12(3):789. doi: 10.3390/nu12030789.

Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases

Mattia Bellan 1 2 3, Laura Andreoli 4, Chiara Mele 1, Pier Paolo Sainaghi 1 2 3, Cristina Rigamonti 1 2 3, Silvia Piantoni 4, Carla De Benedittis 1 2 3, Gianluca Aimaretti 1, Mario Pirisi 1 2 3, Paolo Marzullo 1 5

Affiliations expand

PMID: 32192175  PMCID: PMC7146294  DOI: 10.3390/nu12030789

Studie Hashimoto und Leaky gut

  •  2012 Nov;14(78):321-6. 

Does the gut microbiota trigger Hashimoto's thyroiditis? 

Kouki Mori 1, Yoshinori Nakagawa, Hiroshi Ozaki 

Affiliations expand 

PMID: 23200063 

Studie Hashimoto und POC

  • 2015;40(4):204-10.

 doi: 10.3109/07435800.2015.1015730. Epub 2015 Mar 30.

High prevalence of Hashimoto's thyroiditis in patients with polycystic ovary syndrome: does the imbalance between estradiol and progesterone play a role?

Ayse Arduc 1, Bercem Aycicek Dogan 2, Sevgi Bilmez 3, Narin Imga Nasiroglu 2, Mazhar Muslum Tuna 2, Serhat Isik 2, Dilek Berker 2, Serdar Guler 4

Affiliations expand

PMID: 25822940  DOI: 10.3109/07435800.2015.1015730

Studie Hashimoto, Jod, Selen, Gluten, Vitamin D

  • Jan-Apr 2017;20(1):51-56.

 doi: 10.1967/s002449910507. Epub 2017 Mar 20.

A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients.Points that need more investigation

Michael I Liontiris 1, Elias E Mazokopakis

Affiliations expand

PMID: 28315909  DOI: 10.1967/s002449910507

Studien zu Vitamin D 

  • Heseker H, Adolf T, Eberhardt W, Hartmann S, Herwig A, Kuber W, Matiakse B, Moch

 KJ, Schneider R & Zipp A (1992) Food and nutrient intakes of adults in the German Federal Republic. In VERA-Schriftenriche , vol. 3; pp. 188 – 189 [W Kubler, HJ Anders, W Heeschen and D Kohlmeier, editors]. Neiderkleen: Fleck Verlag.


  • van Dokkum W (1995) The intake of selected minerals and trace elements in European

 countries. Nutrition Research Reviews 8 , 271 – 302


  • Kudlacek, S., Schneider, B., Peterlik, M., Leb, G., Klaushofer, K., Weber, K., Woloszczuk, 

W. and Willvonseder, R. (2003), Assessment of vitamin D and calcium status in healthy adult Austrians. European Journal of Clinical Investigation, 33: 323–331. doi: 10.1046/j.1365-2362.2003.01127.x


  • Portale, A. A., et al. Oral intake of phosphorus can determine the serum concentration 

of 1, 25-dihydroxyvitamin D by determining its production rate in humans. Journal of Clinical Investigation, 1986, 77. Jg., Nr. 1, S. 7.


  • Jono, Shuichi, et al. Phosphate regulation of vascular smooth muscle cell calcification. 

Circulation research, 2000, 87. Jg., Nr. 7, S. e10-e17.


  • Foley, Robert N., et al. Serum phosphorus levels associate with coronary 

atherosclerosis in young adults. Journal of the American Society of Nephrology, 2009, 20. Jg., Nr. 2, S. 397-404.


  • Vermeer C, Jie KS, Knapen MH. Role of vitamin K in bone metabolism. Annu Rev Nutr. 

1995;15:1-22. Review. PubMed PMID: 8527213.


  • Masterjohn C. Vitamin D toxicity redefined: vitamin K and the molecular mechanism.

 Med Hypotheses. 2007;68(5):1026-34. Epub 2006 Dec 4. PubMed PMID: 17145139.


  • Fu X, Wang XD, Mernitz H, Wallin R, Shea MK, Booth SL. 9-Cis retinoic acid reduces 

1alpha,25-dihydroxycholecalciferol-induced renal calcification by altering vitamin K-dependent gamma-carboxylation of matrix gamma-carboxyglutamic acid protein in A/J male mice. J Nutr. 2008 Dec;138(12):2337-41. doi: 10.3945/jn.108.093724. PubMed PMID: 19022954.


  • Berkner, K. L. and Runge, K. W. (2004), The physiology of vitamin K nutriture and 

vitamin K-dependent protein function in atherosclerosis. Journal of Thrombosis and Haemostasis, 2: 2118–2132. doi: 10.1111/j.1538-7836.2004.00968.x


  • Gallop, Paul M., et al. Carboxylated calcium-binding proteins and vitamin K. New 

England Journal of Medicine, 1980, 302. Jg., Nr. 26, S. 1460-1466.


  • P. V. Hauschka, J. B. Lian, D. E. Cole, C. M. Gundberg Osteocalcin and matrix Gla

 protein: vitamin K-dependent proteins in bone Physiological ReviewsJul 1989,69(3)990-1047


  • M.J. Shearer, Vitamin K metabolism and nutriture, Blood Reviews, Volume 6, Issue 2,

 June 1992, Pages 92-104, ISSN 0268-960X, http://dx.doi.org/10.1016/0268-960X(92)90011-E.


  • Biesalski, Hans K. Vitamin D recommendations–beyond deficiency. Annals of Nutrition

 and Metabolism, 2011, 59. Jg., Nr. 1, S. 10-16.


  • R. Sanchez-Martinez, A. I. Castillo, A. Steinmeyer, and A. Aranda, „The retinoid X 

receptor ligand restores defective signalling by the vitamin D receptor,“ EMBO Reports, vol. 7, no. 10, pp. 1030-1034, 200


  • Cannell JJ, Vieth R, Willett W, Zasloff M, Hathcock JN, White JH, Tanumihardjo SA,

 Larson-Meyer DE, Bischoff-Ferrari HA, Lamberg-Allardt CJ, Lappe JM, Norman AW, Zittermann A, Whiting SJ, Grant WB, Hollis BW, Giovannucci E. Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic. Ann Otol Rhinol Laryngol. 2008 Nov;117(11):864-70. Review. PubMed PMID: 19102134.


  • S. Johansson and H. Melhus, „Vitamin A antagonizes calcium response to vitamin D in

 man,“ Journal ofBone and Mineral Research, vol. 16, no. 10, pp. 1899-1905, 2001.


  • Spiesman IG. Massive Doses of Vitamins A and D in the Prevention of the Common

 Cold. Arch Otolaryngol Head Neck Surg. 1941;34(4): 787-791.


  • Sanchez-Martinez R, Castillo A, Steinmeyer A, Aranda A. The retinoid X receptor ligand

 restores defective signaling by the vitamin D receptor. EMBO Rep. 2006;7(10):1030-4.


  • Sánchez-Martínez R, Zambrano A, Castillo AI, Aranda A. Vitamin D-dependent 

recruitment of corepressors to vitamin D/retinoid X receptor heterodimers. Mol Cell Biol. 2008;28(11):3817-29.


  • Rude RK, Adams JS, Ryzen E, Endres DB, Niimi H, Horst RL, Haddad JG Jr, Singer FR.

 Low serum concentrations of 1,25-dihydroxyvitamin D in human magnesium deficiency. J Clin Endocrinol Metab. 1985 Nov;61(5):933-40. PubMed PMID: 3840173.


  • 22. Reddy V, Sivakumar B. Magnesium-dependent vitamin-D-resistant rickets. Lancet.

 1974 May 18;1(7864):963-5. PubMed PMID: 4133647.


  • Zittermann, Armin. Magnesium deficit? overlooked cause of low vitamin D status?.

 BMC medicine, 2013, 11. Jg., Nr. 1, S. 229.


  • Coudray, C., et al. Study of magnesium bioavailability from ten organic and inorganic 

Mg salts in Mg-depleted rats using a stable isotope approach. Magnesium research, 2005, 18. Jg., Nr. 4, S. 215-223.


  • Freedman, Leonard P. Anatomy of the steroid receptor zinc finger region. Endocrine 

reviews, 1992, 13. Jg., Nr. 2, S. 129-145.


  • Freedman, Leonard P.; TOWERS, Terri L. DNA binding properties of the vitamin D3 receptor zinc finger region. Molecular Endocrinology, 1991, 5. Jg., Nr. 12, S. 1815-1826.


  • Hunt, C. D. (1996), Biochemical effects of physiological amounts of dietary boron. J. Trace Elem. Exp. Med., 9: 185–213. doi: 10.1002/(SICI)1520-670X(1996)9:43.0.CO;2-Q


  • Hunt, C. D., Herbel, J. L. and Idso, J. P. (1994), Dietary boron modifies the effects of vitamin D3 nutrition on indices of energy substrate utilization and mineral metabolism in the chick. J Bone Miner Res, 9: 171–182. doi: 10.1002/jbmr.5650090206


  • Miljkovic, D., Miljkovic, N., & McCarty, M. F. . Up-regulatory impact of boron on vitamin D function–does it reflect inhibition of 24-hydroxylase?. Medical hypotheses, 2004, 63. Jg., Nr. 6, S. 1054-1056.


  • Hegsted, Maren, et al. Effect of boron on vitamin D deficient rats. Biological trace element research, 1991, 28. Jg., Nr. 3, S. 243-255.

 

Studien zu Zink  

  • Guttek K, Wagenbrett L, Reinhold A et al.: Zinc aspartate suppresses proliferation and Th1/Th2/Th17 cytokine production of pre-activated human t cells in vitro. J Trace Elem Med Biol. 2018 Sep;49:86-90. DOI: 10.1016/j.jtemb.2018.05.003.


  • https://www.pharmazeutische-zeitung.de/ausgabe-232018/toleranzinduktion-als-option-auf-heilung/


  • Mousavi SM, Djafarian K, Mojtahed A et al: The effect of zinc supplementation on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials. Eur J Pharmacol. 2018 Jul 19;834:10-16.


Studien T3, T4, NDT

Fereidoun Azizi, Atieh Amouzegar, Ladan Mehran, Hengameh Abdi

Int J Endocrinol Metab. 2020 Apr; 18(2): e100870. Published online 2020 Apr 7. doi: 10.5812/ijem.100870

PMCID: PMC7322563 Article PubReader PDF–111KCitation

 

Lewis E. Braverman, Sidney H. Ingbar, Kenneth Sterling

J Clin Invest. 1970 May; 49(5): 855–864. doi: 10.1172/JCI106304

Correction in: J Clin Invest. 1970 Jul; 49(7): 3f.

PMCID: PMC535757  Summary Page Browse PDF–1.7MCitation

 

Freddy J. K. Toloza, Nataly R. Espinoza Suarez, Omar El Kawkgi, Elizabeth H. Golembiewski, Oscar J. Ponce, Lixia Yao, Spyridoula Maraka, Naykky M. Singh Ospina, Juan P. Brito

Medicina (Kaunas) 2020 Apr; 56(4): 161. Published online 2020 Apr 3. doi: 10.3390/medicina56040161

PMCID: PMC7230696  Article PubReader PDF–283KCitation

 

Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone? 

J Clin Endocrinol Metab. 2020 Sep 1;105(9):dgaa430. doi: 10.1210/clinem/dgaa430.

Matthew D Ettleson 1, Antonio C Bianco 1

Affiliations expand

PMID: 32614450 PMCID: PMC7382053 (available on 2021-07-02) 

DOI: 10.1210/clinem/dgaa430


Studien Kurkuma

 https://pubmed.ncbi.nlm.nih.gov/30402990/ 

The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials

Reza Tabrizi 1, Sina Vakili 2, Maryam Akbari 1, Naghmeh Mirhosseini 3, Kamran B Lankarani 1, Maryam Rahimi 4, Moein Mobini 5, Sadegh Jafarnejad 6, Zahra Vahedpoor 7, Zatollah Asemi 6 Affiliations expand PMID: 30402990 DOI: 10.1002/ptr.6226
 

https://pubmed.ncbi.nlm.nih.gov/26007179/ 

Curcumin, inflammation, and chronic diseases: how are they linked? 

Yan He 1, Yuan Yue 2, Xi Zheng 3 4, Kun Zhang 5, Shaohua Chen 6, Zhiyun Du 7 

Affiliations expand PMID: 26007179 PMCID: PMC6272784 
DOI: 10.3390/molecules20059183